Newborn screening for hemoglobinopathies: the benefit beyond the target.
R Grover,
S Newman,
D Wethers,
K Anyane-Yeboa and
K Pass
As a result of New York State's Newborn Screening Program 4,565neonates with trait hemoglobinopathies were identified and 3,200families were notified of the results of testing their infantsin New York City in 1982. Of the 1,531 families (2,190 parents)tested and counseled, 22 parents were diagnosed with sicklecell disease and 39 couples were found to be at-risk for havinga child with sickle cell disease. Amniocentesis was performedin 14 of the 28 at-risk pregnant women and three of the fouraffected pregnancies were terminated. MCH-331001-01 to 04
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