Why genes don't count (for racial differences in health)
AH Goodman
US Southwest and Mexico Program, School of Natural Science, Hampshire College, Amherst, MA 01002, USA. agoodman@hampshire.edu
There is a paradoxical relationship between "race" and genetics. Whereas
genetic data were first used to prove the validity of race, since the early
1970s they have been used to illustrate the invalidity of biological races.
Indeed, race does not account for human genetic variation, which is
continuous, complexly structured, constantly changing, and predominantly
within "races." Despite the disproof of race-as-biology, genetic variation
continues to be used to explain racial differences. Such explanations
require the acceptance of 2 disproved assumptions: that genetic variation
explains variation in disease and that genetic variation explains racial
variation in disease. While the former is a form of geneticization, the
notion that genes are the primary determinants of biology and behavior, the
latter represents a form of racialization, an exaggeration of the salience
of race. Using race as a proxy for genetic differences limits
understandings of the complex interactions among political-economic
processes, lived experiences, and human biologies. By moving beyond studies
of racialized genetics, we can clarify the processes by which varied and
interwoven forms of racialization and racism affect individuals "under the
skin."
This article has been cited by other articles:
D. T. Sanchez and J. A. Garcia When Race Matters: Racially Stigmatized Others and Perceiving Race as a Biological Construction Affect Biracial People's Daily Well-Being
Pers Soc Psychol Bull,
September 1, 2009;
35(9):
1154 - 1164.
[Abstract][PDF]
P. A. Sample, C. A. Girkin, L. M. Zangwill, S. Jain, L. Racette, L. M. Becerra, R. N. Weinreb, F. A. Medeiros, M. R. Wilson, J. De Leon-Ortega, et al. The African Descent and Glaucoma Evaluation Study (ADAGES): Design and Baseline Data
Arch Ophthalmol,
September 1, 2009;
127(9):
1136 - 1145.
[Abstract][Full Text][PDF]
Y. Kelly, L. Panico, M. Bartley, M. Marmot, J. Nazroo, and A. Sacker Why does birthweight vary among ethnic groups in the UK? Findings from the Millennium Cohort Study
J. Public Health Med.,
March 1, 2009;
31(1):
131 - 137.
[Abstract][Full Text][PDF]
W. Anderson Teaching 'race' at medical school: social scientists on the margin.
Social Studies of Science,
October 1, 2008;
38(5):
785 - 800.
[Abstract][PDF]
A. Smart, R. Tutton, P. Martin, G. T.H. Ellison, and R. Ashcroft The standardization of race and ethnicity in biomedical science editorials and UK biobanks.
Social Studies of Science,
June 1, 2008;
38(3):
407 - 423.
[Abstract][PDF]
L M Hunt and M S Megyesi Genes, race and research ethics: who's minding the store?
J. Med. Ethics,
June 1, 2008;
34(6):
495 - 500.
[Abstract][Full Text][PDF]
P. W. Payne Jr and C. Royal The Role of Genetic and Sociopolitical Definitions of Racein Clinical Trials
J. Am. Acad. Ortho. Surg.,
September 1, 2007;
15(suppl_1):
S100 - S104.
[Abstract][Full Text][PDF]
H Shanawani, L Dame, D A Schwartz, and R Cook-Deegan Non-reporting and inconsistent reporting of race and ethnicity in articles that claim associations among genotype, outcome, and race or ethnicity
J. Med. Ethics,
December 1, 2006;
32(12):
724 - 728.
[Abstract][Full Text][PDF]
R. Sterling, G. E. Henderson, and G. Corbie-Smith Public Willingness to Participate in and Public Opinions About Genetic Variation Research: A Review of the Literature
Am J Public Health,
November 1, 2006;
96(11):
1971 - 1978.
[Abstract][Full Text][PDF]
T. R. Rebbeck, C. H. Halbert, and P. Sankar Genetics, Epidemiology, and Cancer Disparities: Is it Black and White?
J. Clin. Oncol.,
May 10, 2006;
24(14):
2164 - 2169.
[Abstract][Full Text][PDF]
J. C. Thomas, D. E. Irwin, E. S. Zuiker, and R. C. Millikan Genomics and the Public Health Code of Ethics
Am J Public Health,
December 1, 2005;
95(12):
2139 - 2143.
[Abstract][Full Text][PDF]
T. R. Rebbeck and P. Sankar Ethnicity, Ancestry, and Race in Molecular Epidemiologic Research
Cancer Epidemiol. Biomarkers Prev.,
November 1, 2005;
14(11):
2467 - 2471.
[Full Text][PDF]
N. Krieger Embodiment: a conceptual glossary for epidemiology
J Epidemiol Community Health,
May 1, 2005;
59(5):
350 - 355.
[Abstract][Full Text][PDF]
G. King, A. Polednak, R. B. Bendel, M. C. Vilsaint, and S. B. Nahata Disparities in Smoking Cessation Between African Americans and Whites: 1990-2000
Am J Public Health,
November 1, 2004;
94(11):
1965 - 1971.
[Abstract][Full Text][PDF]
C. M. Condit, R. L. Parrott, T. M. Harris, J. Lynch, and T. Dubriwny The Role of "Genetics" in Popular Understandings of Race in the United States
Public Understanding of Science,
July 1, 2004;
13(3):
249 - 272.
[Abstract][PDF]
D. R. Williams and C. Collins Reparations: A Viable Strategy to Address the Enigma of African American Health
American Behavioral Scientist,
March 1, 2004;
47(7):
977 - 1000.
[Abstract][PDF]
C. Walsh and L. F. Ross Are Minority Children Under- or Overrepresented in Pediatric Research?
Pediatrics,
October 1, 2003;
112(4):
890 - 895.
[Abstract][Full Text][PDF]
J. B. Kaplan and T. Bennett Use of Race and Ethnicity in Biomedical Publication
JAMA,
May 28, 2003;
289(20):
2709 - 2716.
[Abstract][Full Text][PDF]
M. C. Leske, S.-Y. Wu, B. Nemesure, A. Hennis, and for the Barbados Eye Studies Group Incident Open-Angle Glaucoma and Blood Pressure
Arch Ophthalmol,
July 1, 2002;
120(7):
954 - 959.
[Abstract][Full Text][PDF]
W. B. Sateren, E. L. Trimble, J. Abrams, O. Brawley, N. Breen, L. Ford, M. McCabe, R. Kaplan, M. Smith, R. Ungerleider, et al. How Sociodemographics, Presence of Oncology Specialists, and Hospital Cancer Programs Affect Accrual to Cancer Treatment Trials
J. Clin. Oncol.,
April 15, 2002;
20(8):
2109 - 2117.
[Abstract][Full Text][PDF]
M. A. Austin Ethical Issues in Human Genome Epidemiology: A Case Study Based on The Japanese American Family Study in Seattle, Washington
Am. J. Epidemiol.,
April 1, 2002;
155(7):
585 - 592.
[Abstract][Full Text][PDF]
N. Chaturvedi Ethnicity as an epidemiological determinant--crudely racist or crucially important?
Int. J. Epidemiol.,
October 1, 2001;
30(5):
925 - 927.
[Full Text][PDF]