New NHLBI clinical guidelines for obesity and overweight: will they promote health?
WJ Strawbridge, MI Wallhagen and SJ Shema
Human Population Laboratory, Public Health Institute, Berkeley, CA 94704-1011, USA.
OBJECTIVES: The purpose of this study was to assess the justification, on
the basis of mortality, of the new National Heart, Lung, and Blood
Institute (NHLBI) guidelines on obesity and overweight and to discuss the
health implications of declaring all adults with a body mass index of 25
through 29 "overweight." METHODS: The relationships between NHLBI body mass
index categories and mortality for individuals older than 31 years were
analyzed for 6253 Alameda County Study respondents aged 21 through 75
years. Time-dependent proportional hazards models were used to adjust for
changes in risk factors and weight during follow-up. RESULTS: Adjusted
relative risks of mortality for 4 NHLBI categories compared with the
category "normal" indicated that only being underweight or
moderately/extremely obese were associated with higher mortality. Specific
risk varied significantly by sex. CONCLUSIONS: Our results are consistent
with other studies and fail to justify lowering the overweight threshold on
the basis of mortality. Current interpretations of the revised guidelines
stigmatize too many people as overweight; fail to account for sex,
race/ethnicity, age, and other differences; and ignore the serious health
risks associated with low weight and efforts to maintain an unrealistically
lean body mass.
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