American Journal of Public Health, Vol 90, Issue 6 966-971, Copyright © 2000 by American Public Health Association
Menopausal hormones and breast cancer in a biracial population
PG Moorman, H Kuwabara, RC Millikan and B Newman
Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Conn., USA. patricia.moorman@yale.edu
OBJECTIVES: This study examined the association between menopausal hormones
and breast cancer in a biracial population. METHODS: Logistic regression
was used to calculate odds ratios for breast cancer associated with hormone
use among 397 cases and 425 controls, all menopausal women. RESULTS: Odds
ratios for ever use of hormones were 0.8 (95% confidence interval [CI] =
0.5, 1.2) for White women and 0.7 (95% CI = 0.4, 1.2) for Black women. Risk
was not increased with longer duration of use or more recent use.
CONCLUSIONS: Breast cancer risk was not increased among White or Black
women who used menopausal hormones, despite patterns of use varying
considerably between races.