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Gabriel M. Leung, MD, MPH, Tai-Hing Lam, MD, Thuan Q. Thach, PhD and Anthony J. Hedley, MD

Gabriel M. Leung, Tai-Hing Lam, Thuan Q. Thach, and Anthony J. Hedley are with the Department of Community Medicine, University of Hong Kong Medical Centre, Hong Kong.

Correspondence: Requests for reprints should be sent to G. M. Leung, MD, MPH, Department of Community Medicine, 21 Sassoon Road, Patrick Manson Building, University of Hong Kong, Pokfulam, Hong Kong (e-mail: gmleung{at}hku.hk).

Objectives. We sought to systematically review the evidence for population-based mammography as applied to a Chinese population.

Methods. Primary reports for meta-analysis were identified by a search of MEDLINE and the Cochrane Library. Outcome measures included breast cancer–related mortality, the number needed to be screened to prevent 1 death, and the positive predictive value of mammography.

Results. Pooled relative risk for breast cancer–related death in the screened group was 0.80 (95% confidence interval = 0.71, 0.90). Applied to Hong Kong, this figure translates into a number needed to screen of 1 302 healthy women screened annually for 10 years to prevent 1 death. Conclusions. Evidence is insufficient to justify population-based breast cancer screening by mammography for women in Hong Kong and other Asian populations with low breast cancer prevalence.

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