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Anna C. Mastroianni, JD, MPH and Jeffrey P. Kahn, PhD, MPH

Anna C. Mastroianni is with the University of Washington School of Law and the Institute for Public Health Genetics, Seattle. Jeffrey P. Kahn is with the University of Minnesota Center for Bioethics, Minneapolis.

Correspondence: Requests for reprints should be sent to Jeffrey P. Kahn, PhD, MPH, University of Minnesota Center for Bioethics, N504 Boynton, 410 Church St SE, Minneapolis, MN 55455 (e-mail: kahnx009{at}tc.umn.edu).

The legal case of Grimes v. Kennedy Krieger Institute, Inc, has raised concerns in the public health research community regarding the acceptable level of risk in research involving children, parental authority for informed consent, and exploitation of research subjects for the benefit of public health. We provide an overview of the case and discuss the impact of the court's decision and its possible effect on future research protection policies and practices. (Am J Public Health. 2002;92:1073–1076)

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