Environmental Tobacco Smoke and Adult-Onset Asthma: A Population-Based Incident CaseControl Study
Maritta S. Jaakkola, MD, DSc,
Ritva Piipari, MD,
Niina Jaakkola, PhD and
Jouni J. K. Jaakkola, MD, PhD
Maritta S. Jaakkola and Ritva Piipari are with the Finnish Institute of Occupational Health, Helsinki, Finland. Niina Jaakkola is with the Environmental Epidemiology Unit, Department of Public Health, University of Helsinki. At the time of the study, Jouni J. K. Jaakkola was with the Environmental Health Program, Nordic School of Public Health, Göteborg, Sweden.
Correspondence: Requests for reprints should be sent to Maritta S. Jaakkola, MD, DSc, Institute of Occupational Health, the University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom (e-mail: M.Jaakkola{at}bham.ac.uk).
Objectives. The authors assessed the effects of environmentaltobacco smoke (ETS) on the development of asthma in adults.
Methods. In the Pirkanmaa district of South Finland, all 21-to 63-year-old adults with new cases of asthma diagnosed duringa 2.5-year period (n = 521 case patients, out of 441 000 inhabitants)and a random sample of control subjects from the source population(932 control subjects) participated in a population-based incidentcasecontrol study.
Results. Risk of asthma was related to workplace ETS exposure(adjusted odds ratio [OR] = 2.16; 95% confidence interval [CI]= 1.26, 3.72) and home exposure (OR = 4.77; 95% CI = 1.29, 17.7)in the past year. Cumulative ETS exposure over a lifetime atwork and at home increased the risk.
Conclusions. This study indicates for the first time that bothcumulative lifetime and recent ETS exposures increase the riskof adult-onset asthma.
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