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Kristina M. Zierold, PhD, Lynda Knobeloch, PhD and Henry Anderson, MD

Kristina M. Zierold is with the Department of Environmental Health Sciences, Arnold School of Public Health, University of South Carolina, Columbia. Lynda Knobeloch and Henry Anderson are with the Wisconsin Division of Public Health, Bureau of Environmental Health, Madison.

Correspondence: Requests for reprints should be sent to Kristina M. Zierold, PhD, Department of Environmental Health Sciences, Arnold School of Public Health, 800 Sumter St, University of South Carolina, Columbia, SC 29208 (e-mail: zierold{at}gwm.sc.edu).

Inorganic arsenic is naturally occurring in groundwaters throughout the United States. This study investigated arsenic exposure and self-report of 9 chronic diseases. We received private well-water samples and questionnaires from 1185 people who reported drinking their water for 20 or more years. Respondents with arsenic levels of 2 µg/L or greater were statistically more likely to report a history of depression, high blood pressure, circulatory problems, and bypass surgery than were respondents with arsenic concentrations less than 2 µg/L.

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