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March 2004, Vol 94, No. 3 | American Journal of Public Health 361-366
© 2004 American Public Health Association

COMMENTARY

Improving the Reporting Quality of Nonrandomized Evaluations of Behavioral and Public Health Interventions: The TREND Statement

Don C. Des Jarlais, PhD, Cynthia Lyles, PhD, Nicole Crepaz, PhD and the TREND Group

Don C. Des Jarlais is with the Baron Edmond de Rothschild Chemical Dependency Institute, Beth Israel Medical Center, New York City. Cynthia Lyles and Nicole Crepaz are with the Centers for Disease Control and Prevention, Atlanta, Ga. TREND Group members are listed below in the Acknowledgments.

Correspondence: Requests for reprints should be sent to Don C. Des Jarlais, PhD, Beth Israel Medical Center, Chemical Dependency Institute, First Ave at 16 St, New York, NY 10003 (e-mail: dcdesjarla{at}aol.com).

Developing an evidence base for making public health decisions will require using data from evaluation studies with randomized and nonrandomized designs. Assessing individual studies and using studies in quantitative research syntheses require transparent reporting of the study, with sufficient detail and clarity to readily see differences and similarities among studies in the same area. The Consolidated Standards of Reporting Trials (CONSORT) statement provides guidelines for transparent reporting of randomized clinical trials.

We present the initial version of the Transparent Reporting of Evaluations with Nonrandomized Designs (TREND) statement. These guidelines emphasize the reporting of theories used and descriptions of intervention and comparison conditions, research design, and methods of adjusting for possible biases in evaluation studies that use nonrandomized designs.




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