Impact of PCV7 on Invasive Pneumococcal Disease Among Children Younger Than 5 Years: A Population-Based Study
Revathi R. Ramani, MD, MPH,
William N. Hall, MD, MPH,
Matthew Boulton, MD, MPH,
David R. Johnson, MD, MPH and
Bao-Ping Zhu, MD, MS
At the time of the study, all the authors were with the Michigan Department of Community Health, Lansing, Mich. Revathi R. Ramani and Matthew Boulton also were with the University of Michigan Preventive Medicine Residency Program, Ann Arbor.
Correspondence: Requests for reprints should be sent to William N. Hall, Bureau of Epidemiology, Mich Dept of Community Health, 3423 N Martin Luther King Blvd, Lansing, MI 48909 (e-mail: hallw{at}michigan.gov).
We examined the impact of the heptavalent pneumococcal conjugatevaccine (PCV7) on hospital discharge rates for invasive pneumococcaldisease among Michigan children younger than 5 years old. Afterthe introduction of PCV7, the hospital discharge rate for childrenyounger than 1 years old was significantly lower than beforeintroduction. We correlated the decreased rates with the introductionand rapid uptake of PCV7. Lack of change in the hospital dischargerates for other age groups likely represents a slower uptakeof PCV7 compared with that for children aged younger than 1year.
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