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Judith J. Prochaska, PhD, MPH, Sharon M. Hall, PhD, Janice Y. Tsoh, PhD, Stuart Eisendrath, MD, Joseph S. Rossi, PhD, Colleen A. Redding, PhD, Amy B. Rosen, PsyD, Marc Meisner, MD, Gary L. Humfleet, PhD and Julie A. Gorecki, MA

Judith J. Prochaska, Sharon M. Hall, Janice Y. Tsoh, Stuart Eisendrath, Gary L. Humfleet, and Julie A. Gorecki are with the University of California, San Francisco. Joseph S. Rossi and Colleen A. Redding are with the University of Rhode Island Cancer Prevention Research Center, Kingston. At the time of this study, Amy B. Rosen was with the University of California, San Francisco. Marc Meisner is with Kaiser Permanente, San Rafael, Calif.

Correspondence: Requests for reprints should be sent to Judith J. Prochaska, PhD, MPH, University of California-San Francisco, 401 Parnassus Ave, Box TRC–0984, San Francisco, CA 94143–0984 (e-mail: jprochaska{at}ucsf.edu).

We analyzed data from a randomized trial of 322 actively depressed smokers and examined the effect of smoking cessation on their mental health functioning. Only 1 of 10 measures at 4 follow-up time points was significant: participants who successfully stopped smoking reported less alcohol use than did participants who continued smoking. Depressive symptoms declined significantly over time for participants who stopped smoking and those who continued smoking; there were no group differences. Individuals in treatment for clinical depression can be helped to stop smoking without adversely affecting their mental health functioning.

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