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AJPH First Look, published online ahead of print Oct 15, 2009
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December 2009, Vol 99, No. 12 | American Journal of Public Health 2184-2187
© 2009 American Public Health Association
DOI: 10.2105/AJPH.2009.159889


RESEARCH AND PRACTICE

Changes in Postmenopausal Hormone Replacement Therapy Use Among Women With High Cardiovascular Risk

Angela Hsu, MD, Andrea Card, MD, Susan Xiaoqin Lin, DrPH, Sean Mota, BA, Olveen Carrasquillo, MD, MPH and Andrew Moran, MD, MPH

All authors are with Columbia Presbyterian Medical Center, New York, NY.

Correspondence: Correspondence can be sent to Andrew Moran, MD, MPH, Division of General Internal Medicine, PH 9 East Room 105, 622 W 168th St, New York, NY 10032 (e-mail: aem35{at}columbia.edu). Reprints can be ordered at http://www.ajph.org by clicking the "Reprints/Eprints" link.

After randomized trials failed to support the use of hormone replacement therapy (HRT) for preventing cardiovascular disease (CVD), HRT use for postmenopausal women declined. Our analysis of 1999–2000 and 2003–2004 National Health and Nutrition Surveys (NHANES) shows that HRT use decreased 19% (from 27.6 to 8.4%; P < .001) among women with CVD versus 3% (from 19.8 to 16.8%; P = .68) among low-risk women, suggesting that most of the drop in HRT use may be among women prescribed HRT as an unproven treatment to prevent CVD.







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