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AJPH First Look, published online ahead of print Dec 4, 2008
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February 2009, Vol 99, No. 2 | American Journal of Public Health 340-347
© 2009 American Public Health Association
DOI: 10.2105/AJPH.2007.129528


RESEARCH AND PRACTICE

Highly Active Antiretroviral Therapy and Increased Use of Contraceptives Among HIV-Positive Women During Expanding Access to Antiretroviral Therapy in Mbarara, Uganda

Irene Andia, MB, ChB, MMed, Angela Kaida, MSc, Marissa Maier, MD, David Guzman, MSPH, Nneka Emenyonu, MPH, Larry Pepper, DO, MSPM, David R. Bangsberg, MD, MPH and Robert S. Hogg, PhD

Irene Andia is with the Department of Internal Medicine, Mbarara University of Science and Technology, Mbarara, Uganda. Angela Kaida is with the Department of Health Care and Epidemiology, Faculty of Medicine, University of British Columbia, Vancouver. Marissa Maier is with the Department of Internal Medicine, Oregon Health & Science University, Portland. David Guzman and Nneka Emenyonu are with the Department of Internal Medicine, University of California, San Francisco. Larry Pepper is with the Mbarara University of Science and Technology, Mbarara. David R. Bangsberg is with Harvard Medical School/Massachusetts General Hospital, Boston. Robert S. Hogg is with the BC Centre for Excellence in HIV/AIDS, Vancouver.

Correspondence: Requests for reprints should be sent to Irene Andia, MB, ChB, MMed, Mbarara University of Science and Technology, PO Box 1410, Mbarara, Uganda (e-mail: andiaodanga{at}yahoo.com).

Objectives. We investigated whether the prevalence of contraceptive use among women who are HIV positive varied according to use of highly active antiretroviral therapy (HAART) in Mbarara, Uganda.

Methods. We used data from a cross-sectional survey of 484 women who were HIV positive (18–50 years) and were attending Mbarara University's HIV clinic, 45% of whom were receiving HAART. Multivariate logistic regression was used to investigate the association between HAART use and contraceptive use. Data were collected between November 2005 and June 2006.

Results. Overall, 45% of the women were sexually active in the previous 3 months. Of these, 85% reported using contraceptive methods, with 84% reporting use of barrier contraceptive methods. Women receiving HAART were more than twice as likely to use contraceptive methods (adjusted odds ratio [AOR] = 2.64; 95% confidence interval [CI] = 1.07, 6.49) and more than 3 times as likely to use barrier contraceptive methods (AOR = 3.62; 95% CI = 1.54, 8.55) than were women not receiving HAART.

Conclusions. Our findings support the need for increased attention to better integration of reproductive health and HIV and AIDS services for women who are HIV positive.







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