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AJPH First Look, published online ahead of print Jan 15, 2009
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March 2009, Vol 99, No. 3 | American Journal of Public Health 402-407
© 2009 American Public Health Association
DOI: 10.2105/AJPH.2008.136937


HEALTH POLICY AND ETHICS

Expanded Access to Naloxone: Options for Critical Response to the Epidemic of Opioid Overdose Mortality

Daniel Kim, MPH, Kevin S. Irwin, MA and Kaveh Khoshnood, PhD

Daniel Kim is with the American Medical Association, Chicago, IL. Kevin S. Irwin is with the Community Health Program, Tufts University, Boston, MA. Kaveh Khoshnood is with the Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT.

Correspondence: Requests for reprints should be sent to Kaveh Khoshnood, PhD, Department of Epidemiology and Public Health, Yale University School of Medicine, 60 College Street #405, New Haven, CT 06520 (e-mail: kaveh.khoshnood{at}yale.edu).

The United States is in the midst of a prolonged and growing epidemic of accidental and preventable deaths associated with overdoses of licit and illicit opioids. For more than 3 decades, naloxone has been used by emergency medical personnel to pharmacologically reverse overdoses. The peers or family members of overdose victims, however, are most often the actual first responders and are best positioned to intervene within an hour of the onset of overdose symptoms.

Data from recent pilot programs demonstrate that lay persons are consistently successful in safely administering naloxone and reversing opioid overdose. Current evidence supports the extensive scaleup of access to naloxone. We present advantages and limitations associated with a range of possible policy and program responses.







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