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AJPH First Look, published online ahead of print Jun 18, 2009
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AJPH.2008.142166v1
99/8/1491    most recent
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August 2009, Vol 99, No. 8 | American Journal of Public Health 1491-1495
© 2009 American Public Health Association
DOI: 10.2105/AJPH.2008.142166


RESEARCH AND PRACTICE

Influences of Cross-Border Mobility on Tuberculosis Diagnoses and Treatment Interruption Among Injection Drug Users in Tijuana, Mexico

Robert Deiss, MD, Richard S. Garfein, PhD, Remedios Lozada, MD, Jose Luis Burgos, MD, Kimberly C. Brouwer, PhD, Kathleen S. Moser, MD, Maria Luisa Zuniga, PhD, Timothy C. Rodwell, MD, Victoria D. Ojeda, PhD and Steffanie A. Strathdee, PhD

Robert Deiss, Richard S. Garfein, Jose Luis Burgos, Kimberly C. Brouwer, Maria Luisa Zuniga, Timothy C. Rodwell, Victoria D. Ojeda, and Steffanie A. Strathdee are with the Department of Family and Preventive Medicine, Division of International Health and Cross-Cultural Medicine, School of Medicine, University of California, San Diego. Remedios Lozada is with Patronato Pro-Comusida, Tijuana, Mexico. Kathleen S. Moser is with the County of San Diego Health and Human Services Agency, San Diego.

Correspondence: Correspondence should be sent to Steffanie A. Strathdee, PhD, 9500 Gilman Dr, Mailstop 0622, La Jolla, CA 92093 (e-mail: sstrathdee{at}ucsd.edu). Reprints can be ordered at http://www.ajph.org by clicking on the "Reprints/Eprints" link.

Objectives. We sought to identify correlates of reported lifetime diagnoses of TB among injection drug users in the border city of Tijuana, Mexico.

Methods. Injection drug users in Tijuana were recruited into a prospective cohort study during 2006 and 2007. We used weighted multivariate logistic regression to identify correlates of TB diagnoses.

Results. Of the 1056 participants, 103 (9.8%) reported a history of TB, among whom 93% received anti-TB medication and 80% were diagnosed in the United States. Treatment was prematurely halted among 8% of patients; deportation from the United States was the cause of half of these treatment interruptions. History of travel to (odds ratio [OR] = 6.44; 95% confidence interval [CI] = 1.53, 27.20) or deportation from (OR = 1.83; 95% CI = 1.07, 3.12) the United States and incarceration (OR = 2.20; 95% CI = 1.06, 4.58) were independently associated with a reported lifetime diagnosis of TB.

Conclusions. Mobility and migration are important factors in identifying and treating TB patients diagnosed in the US–Mexico border region. Strengthening capacity on both sides of the border to identify, monitor, and treat TB is a priority.







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