© 2003 American Public Health Association
Cande V. Ananth is with the Section of Epidemiology and Biostatistics, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School/Saint Peters University Hospital, New Brunswick. Cande V. Ananth and Kitaw Demissie are with the Division of Epidemiology, University of Medicine and Dentistry of New JerseySchool of Public Health, New Brunswick. Michael S. Kramer is with the Departments of Pediatrics and of Epidemiology and Biostatistics, McGill University Faculty of Medicine, Montreal, Quebec, Canada. Anthony M. Vintzileos is with the Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School/Saint Peters University Hospital, New Brunswick. Correspondence: Requests for reprints should be sent to Cande V. Ananth, PhD, MPH, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, 125 Paterson St, New Brunswick, NJ 08901-1977 (e-mail: ananthcv@epi.umdnj.edu).
Low birthweight (< 2500 g) is a strong predictor of infant mortality.1 However, low birthweight may be the consequence of preterm birth or restricted fetal growth. During the past 2 decades, preterm birth rates have been increasing in developed countries,29 whereas population-based trends in small-for-gestational-age (SGA) births in the United States remain unexplored. Trends in SGA births are important because the severely growth restricted are at increased risk for infant death,10 whereas less severe cases may lead to permanent deficits in growth and neurocognitive development in later childhood11 and increased risk for adult chronic diseases.12
We performed this study to
| |||||||||||||||||||||||||||||||||||||||