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This issue of the Journalhighlights the challenges of health promotion and disease preventionin a world increasingly defined by global brands, porous borders,instant messaging, and economic interdependencies. Turning thesenew technologies and economic realities into opportunities forbold action and science-based interventions is the work at hand.Worldwide, there are an estimated 1.3 billion smokers, and by2030 tobacco will have become the leading cause of preventabledeath and disability, responsible for an estimated 10 milliondeaths annually. To halt this epidemic, we must find the politicalwill, international leadership, and funding to put tobacco prevention,care, and . . . [Full Text]