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AJPH First Look, published online ahead of print Jun 18, 2009
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AJPH.2009.162008v1
99/8/1349    most recent
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August 2009, Vol 99, No. 8 | American Journal of Public Health 1349-1350
© 2009 American Public Health Association
DOI: 10.2105/AJPH.2009.162008

LETTERS

CARRIER DETECTION AND CLINICAL UNCERTAINTY: THE CASE FOR PUBLIC HEALTH ETHICS

Fiona Alice Miller, PhD, Robin Z. Hayeems, PhD and Jason Scott Robert, PhD

Fiona A. Miller and Robin Z. Hayeems are with the Department of Health Policy, Management and Evaluation, University of Toronto, Toronto. Jason Scott Robert is with the Center for Biology and Society and the School of Life Sciences, Arizona State University, Tempe, and the Department of Basic Medical Sciences, College of Medicine, University of Arizona, Phoenix.

Correspondence: Correspondence should be sent to Dr. Fiona A. Miller, Department of Health Policy, Management and Evaluation, Faculty of Medicine, University of Toronto, 155 College Street, 4th Floor, Toronto, ON, M5T 3M6 (e-mail: fiona.miller@utoronto.ca). Reprints can be ordered at http://www.ajph.org by clicking the "Reprints/Eprints" link.

Because this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

In their response to our commentary, Ross and Clayton provide a clinical rationale for the disclosure of carrier status results generated incidentally through newborn screening for sickle cell disorders, suggesting that carriers are at increased risk for heat stroke in extreme conditions.1 A better case for nondisclosure, they argue, might be made for carrier status for cystic fibrosis, as there are no data to suggest that cystic fibrosis carriers bear health risks.1 We welcome the opportunity to respond.

Our commentary was written in response to existing debates that assume the benign nature of carrier status. Guiding documents2–4 have not suggested . . . [Full Text]






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