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The Impact of the Increasing Number of Multiple Births on the Rates of Preterm Birth and Low Birthweight: An International Study

Béatrice Blondel, PhD, Michael D. Kogan, PhD, Greg R. Alexander, MPH, ScD, Nirupa Dattani, MS, MPhil, Michael S. Kramer, MD, Alison Macfarlane, CStat and Shi Wu Wen, PhD

Béatrice Blonde is with the Epidemiological Research Unit on Perinatal Health and Women’s Health, National Institute for Health and Medical Research, Villejuif, France. Michael D. Kogan is with the Maternal and Child Health Bureau, Health Resources and Services Administration, Rockville, Md. Greg R. Alexander is with the Department of Maternal and Child Health, University of Alabama at Birmingham. Nirupa Dattani is with the Office for National Statistics, London, England. Michael S. Kramer is with the Department of Pediatrics and the Department of Epidemiology and Biostatistics, McGill University, Montreal, Quebec. Alison Macfarlane is with the National Perinatal Epidemiology Unit, Oxford, England. Shi Wu Wen is with the Bureau of Reproductive and Child Health, Centre for Healthy Human Development, Md. Greg R. Alexander is with the Department of Maternal and Child Health, University of Alabama at Birmingham. Nirupa Dattani is with the Office for National Statistics, London, England. Michael S. Kramer is with the Department of Pediatrics and the Department of Epidemiology and Biostatistics, McGill University, Montreal, Quebec. Alison Macfarlane is with the National Perinatal Epidemiology Unit, Oxford, England. Shi Wu Wen is with the Bureau of Reproductive and Child Health, Centre for Healthy Human Development, Ottawa, Ontario.




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FIGURE 1 —Trends in twin and triplet or higher-order births (rates per 1000 live births).

 





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