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Ongoing Transmission of Hepatitis B Virus Infection Among Inmates at a State Correctional Facility

Amy J. Khan, MD, MPH, Edgar P. Simard, MPH, William A. Bower, MD, Heather L. Wurtzel, MPH, Marina Khristova, PhD, Karla D. Wagner, MA, Kathryn E. Arnold, MD, Omana V. Nainan, PhD, Madeleine LaMarre, MN, CFNP and Beth P. Bell, MD, MPH

At the time of this study, Amy J. Khan and Karla D. Wagner were with the Division of Viral Hepatitis, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Ga. Edgar P. Simard, William A. Bower, Heather L. Wurtzel, Marina Khristova, Omana V. Nainan, and Beth P. Bell are with the Division of Viral Hepatitis, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta. Kathryn E. Arnold is with the Division of Public Health, Georgia Department of Human Resources, Atlanta. At the time of this study, Madeleine LaMarre was with the Georgia Department of Corrections, Atlanta.



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  		FIGURE 1—— Genetic relatedness of hepatitis B virus (HBV) DNA from infected inmates: phylogenetic distribution derived from 145-base-pair segment from the surface antigen region.

Note. Samples designated with prefix "1" were collected during the baseline serological survey in June 2000; those with prefix "2" were collected during June 2001. The horizontal line at bottom left represents 1% nucleotide substitution for that horizontal branch length. HBV genotype reference strains were obtained from GenBank (accession numbers AJ309369 for genotype A, AY167098 for genotype B, and AB033558 for genotype D).

 




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