Vincent R Racaniello, Professor Columbia University College of Physicians & Surgeons
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Re: Correction to "Passive Immunization Against Poliomyelitis"
vrr1{at}columbia.edu Vincent R Racaniello
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In his article entitled "Passive Immunization Against Poliomyelitis",
Charles
Rinaldo, referring to the state of poliomyelitis in the U.S., writes that
"Today,
there are fewer than 5 cases a year in the United States, all owing to
vaccine
strain revertents and none causing paralysis." This statement is incorrect
on two
counts. Since January 1, 2000, only IPV has been used in the U.S., and no
vaccine-associated cases have been reported. Vaccine-associated cases of
polio
are identified in part by flaccid paralysis; to write that vaccine strain
revertants
have lead today to 5 cases a year without causing paralysis is a
contradiction.
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