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Volume 101, Issue 4 (April 2011)


Accepted on: Jul 20, 2010

Surviving Drug Addiction: The Effect of Treatment and Abstinence on Mortality

Christy K. Scott, PhD, Michael L. Dennis, PhD, Alexandre Laudet, PhD, Rodney R. Funk, BS, and Ronald S. Simeone, PhD

Christy K. Scott is with the Lighthouse Institute, Chestnut Health Systems, Chicago, IL. Michael L. Dennis is with the Global Appraisal of Individual Needs Coordinating Center, Chestnut Health Systems, Normal, IL. Alexandre Laudet is with the Institute for Research, Education, and Training in Addictions, Pittsburgh, PA. Rodney R. Funk is with Chestnut Health Systems, Normal, IL. Ronald S. Simeone is with Simeone Associates, Albany, NY.

Correspondence should be sent to Christy K. Scott, PhD, Chestnut Health Systems, 221 W Walton, Chicago, IL 60610 (e-mail: ). Reprints can be ordered at http://www.ajph.org by clicking on the “Reprints/Eprints” link.

Peer Reviewed

Contributors

C. K. Scott led the study and the development of the article. C. K. Scott, M. L. Dennis, and A. Laudet reviewed the literature. M. L. Dennis and R. S. Simeone developed the conceptual and analytic plan. M. L. Dennis and R. R. Funk conducted the data analysis. C. K. Scott, M. L. Dennis, and A. Laudet collaborated on conclusions, implications, and the final version of the article.



ABSTRACT

Objectives. We examined the relationships between substance abuse treatment, abstinence, and mortality in a sample of individuals entering treatment. We also estimated overall mortality rates and the extent to which they varied according to demographic, clinical severity, and treatment variables.

Methods. We used data from a 9-year longitudinal study of 1326 adults entering substance abuse treatment on the west side of Chicago, of whom 131 died (11.0 per 1000 person-years). Baseline predictors, initial and long-term treatment response, and substance use patterns were used to predict mortality rates and time to mortality.

Results. Older age, health problems, and substance use were associated with an increased risk of mortality, and higher percentages of time abstinent and longer durations of continuous abstinence were associated with a reduced risk of mortality. Treatment readmission in the first 6 months after baseline was related to an increased likelihood of abstinence, whereas readmission after 6 months was related to a decreased likelihood of abstinence, suggesting that treatment timing is significant.

Conclusions. Our findings suggest the need to shift the addiction treatment field from an acute care model to a chronic disease management paradigm and the need for more aggressive screening, intervention, and addiction management over time.